Show more AllianThera Biopharma headquarters is in Suzhou, Jiangsu. -, Nagano T, Tachihara M, Nishimura Y. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. . AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. Senior Scientist 5 jobs; AllianThera Biopharma Locations. Bookshelf As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. PEM-induced immunogenicity is restrained by CD73. Suzhou, Jiangsu Unauthorized use of these marks is strictly prohibited. Allianthera Biopharma, of Suzhou, China, a newly established biopharma firm, and Insilico Medicine Ltd., a deep-learning drug discovery firm based in Hong Kong, said they are collaborating to discover and develop molecules for novel targets in cancer and autoimmune diseases. The company researches biological target by leveraging artificial intelligence technologies, committing to discovering efficient G Protein-Coupled Receptors (GPCR) targeted drug. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. Clipboard, Search History, and several other advanced features are temporarily unavailable. Investors & Media. If this sounds like you, please get in touch with us. official website and that any information you provide is encrypted GSK shows that Cabenuva every two months is as good as daily Biktarvy, but Gilead looks to go even longer. This site needs JavaScript to work properly. Copyright 20082023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc. Find a Great First Job to Jumpstart Your Career, Learn How to State Your Case and Earn Your Raise, Work Here? -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Insilico Medicine Inc. AllianThera Biopharma. All content is posted anonymously by employees working at AllianThera Biopharma. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry," said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Significance: 2009 Jul;10(4):281-9. doi: 10.3816/CLC.2009.n.039. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and 1F C1, No. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. China. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Design Therapeutics to Participate in the SVB Securities Virtual Global Biopharma Conference. National Library of Medicine 328 Xinghu Street, Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Advanced Search Title. This is the AllianThera Biopharma company profile. Using a physiologic antigen recognition model, inactivation of CD73 significantly increased antigen-specific CD8+ T-cell immunogenicity following PEM treatment. Chills in the biopharma M&A market are frequently blamed on the FTC. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . Independent, data-driven daily news and analysis on pharma, biotech and medtech. and transmitted securely. Epub 2016 Sep 9. Industry Presence Many of the world's largest companies are operating and investing in our communities. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. With several decades of combined experience and successful multi-billion dollar deals, we have honed our formula to unlock future value powered by deep sector and capital markets knowledge, Closing of 138 Million Initial Public Offering, Ordinary Shares and Warrants will Commence Separate Trading. Stockhouse.com uses cookies on this site. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture andKatai Capital. Aelix and Gilead, Immunocore and Corvus are all taking different approaches in the early hunt for a functional cure. General. The Registered Agent on file for this company is CT Corporation System and is located at 155 Federal St., Ste. In this lecture, Dr. Levitt describes how the work he began over 50 years ago has been vastly improved and expanded through the massive increase in computer speed and incredible advances in machine learning. view more. HHS Vulnerability Disclosure, Help Cancer Lett. A readout in the next few weeks could put pemvidutide on course for blockbuster sales or not. Create an account I forgot my password I forgot my password Disclaimer: AAAS and EurekAlert! The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 9 Guanghua Road, Chaoyang District, Beijing. BioWorld Briefs Other news to note Coronavirus Design Therapeutics. Pemetrexed (PEM), which is commonly used following EGFR-TKI treatment failure, was identified as an effective potentiator of STING-dependent TBK1-IRF3-STAT1 signaling in MET-amplified, EGFR-TKI-resistant cells. Sorry, we didn't find any related vantage articles. A biparatopic antibody-drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET pathway blockade. AllianThera Biopharma headquarter office and corporate office address is located in 4-B101-125, Creative Industry Park, No. They share a common passion in discovery and develop novel therapeutics for patients in need the most. Recently, Insilico Medicine secured $37 million in series B funding. Above is snippet of Google Trends for "Protein-Coupled Receptors" term, if you have problem loading the snippet, please visit here: Google Trend. At Recludix, we are innovators and inventors. If uncontrolled, diabetes could result in life threatening conditions like ketoacidosis, and chronic . By using this site, you agree that we may store and access cookies on your device. Suzhou Tianma Group Tianji Bio-Pharmaceutical Company. . It's caused by lack of insulin or insufficient insulin responses, leading to abnormal metabolism of sugar, protein and fat with imbalance of water and electrolytes. The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. -. N Engl J Med 2018;378:11325. Changes wont be saved until you sign up for an Enhanced Profile subscription. Business Type Drug Discovery Country China Founded 2020 ( 3 years old in 2023 ) Company Focus Federal government websites often end in .gov or .mil. Terms were not disclosed. However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. The .gov means its official. 8600 Rockville Pike AllianThera Biopharma is in the sectors of: Pharma. Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. Disclaimer. 2019 Oct;21(10):1287-1301. doi: 10.1007/s12094-019-02075-1. Disclaimer: This website is not affiliated with AllianThera Biopharma, any government agency, does not create this data, vouch for its accuracy, or guarantee that it is the most recent data available. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China R&D. The company's File Number is listed as 001497025. Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveraging unique strengths in different geographies, East or West. PMID: 36066413 DOI: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients. "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. Eccogene is specialized in disease biology, medicinal chemistry, and . GT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based our proprietary TriKE NK cell . are not responsible for the accuracy of news releases posted to EurekAlert! Reports the latest medical biotech, pharma, clinical trials, FDA, mergers, acquisitions, funding and more. 4-B101-125, Creative Industry Park, No. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. Close Appointment form contact@ai-biopharma.com Categories Home Company Services Pipeline News & Events Contact We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry," said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. Clin Transl Oncol. In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. Careers. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. Welcome to the Society for Clinical Trials (SCT). Website http://insilico.com/. For more valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare or similar services. Copyright 2017-2022 Alpha Biopharma Ltd. All rights reserved. Learn More We are an end-to-end, artificial intelligence-driven pharma-technology company with a mission to accelerate drug discovery and development by leveraging our rapidly evolving, proprietary platform across biology, chemistry and clinical development. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. A, TCR expression, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. Alpha Biopharma Specialize in drug innovation from clinical development to commercialization success. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Win whats next. But is the agency really stopping deals from happening? Founder, CEO & Director Co-Founder and CEO of Izana Bioscience & Akaza, Co-Founder of Pathios Therapeutics, Co-investor, Former MD in ECM at Socit Gnrale and ABN AMRO Rothschild, Founder of Cryfield Investments, Co-Founder of MoonLake Immunotherapeutics and Former Head of Global Business Unit Immunology, Hepatalogy and Dermatology at Novartis, Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme, Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs, JATT Acquisition Corp. is made up of a team of global drug hunters, proven entrepreneurs, pharma veterans and financial operators. Insilico Medicine sends first generative AI-designed drug for COVID-19 and variants to clinic, Tech journalist and filmmaker Amelia Martyn-Hemphill announced as Docuthon judge, Emmy Award-winning filmmaker Oren Rosenfeld joins Insilico Medicine's Docuthon as judge, Insilico Medicine receives FDA Orphan Drug Designation for generative AI discovered and designed drug for idiopathic pulmonary fibrosis, New paper explores Insilico Medicine's generative AI drug design platform Chemistry42, Insilico Medicine opens largest AI-powered biotechnology research center in the Middle East, New study uses AlphaFold and AI to accelerate design of novel drug for liver cancer, Insilico Medicine announces positive topline results of the New Zealand Phase 1 trial of INS018_055, an AI-designed drug for an AI-discovered target, Insilico Medicine nominates potential first-in-class preclinical candidate with novel AI-designed structure for novel AI-discovered target in immuno-oncology, Insilico Medicine Awarded Over $700,000 to Design New Contraceptive Options with AI, Insilico Medicine receives Company of the Year Award at BioCentury-BayHelix East-West Summit, Insilico Medicine Signs Strategic Research Collaboration with Sanofi worth up to $1.2 Billion, Deepfake Technology in Drug Design. Cells 2018;7:212. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone alicia@thrustsc.com. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. Please enable it to take advantage of the complete set of features! 2023 SignalHire.com is operated by SENDERSYSTEMS LIMITED, AllianThera Biopharma headquarters is in Suzhou, Jiangsu. A, Schematic, Impaired T-cell antigen-specific recognition of, Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. Explore the options below to learn more about how you can get involved. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. Terms and Conditions I agree to the terms of the Usage AgreementI agree to the terms of the Privacy Policy Create My Account Site Map Terms of Use Privacy Policy Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. Check out our current opportunities and apply today! Vantage homepage Search articles Our latest articles February 10, 2023 328 Xinghu Street What you see here scratches the surface Request a free trial Systematic genomic analyses and cell line studies confirmed upregulation of CD73 in MET-amplified and MET-activated lung cancer contexts, which depends on coinduction of FOSL1. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. 328 Xinghu Street Developer of GPCR-targeted drug. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . An official website of the United States government. Efforts to enhance the immunogenicity of EGFR-mutated lung cancer have been unsuccessful to date. by contributing institutions or for the use of any information through the EurekAlert system. Linkedin. Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and Unable to load your collection due to an error, Unable to load your delegates due to an error. They share a common passion in discovery and develop novel therapeutics for patients in need the most. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. Founded in 2020. Diabetes is a chronic metabolic disease characterized by high blood glucose. government site. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. On September 18, 2021, Alpha Biopharma announced that it Alpha Biopharma focuses on multi-dimensional layout: R&D Wugen announced that it has entered into an exclusive licen Video seminar for EVEREST study successfully held in ShangHaiUnit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, BeiJingRoom 2512, The Place Tower, No. :1287-1301. doi: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients development to commercialization success info. 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